The Latest In Wrinkle Reduction
The FDA has approved Dysport to treat forehead wrinkles and frown lines, making it the second drug to be approved by the agency as a wrinkle treatment.
Dysport (formerly known as Reloxin) is made from the same active ingredient as Botox (made by Allergan), Clostridium botulinim toxin type A. Botulinum toxins, when injected directly into the muscle you wish to affect, temporarily reduce the appearance of wrinkles by restricting the muscle actions that cause creasing and frown lines.
Like Botox, Dysport is administered via an injection at the site of forehead wrinkles. According to Ipsen Biopharm Ltd., which makes Dysport, the FDA based its approval on clinical trials involving about 2,900 people at 80 study sites.
One clinical trial showed 93%-95% of participants noticed an improvement in the appearance of forehead wrinkles within seven days after treatment, and multiple treatments produced effects that lasted for more than 13 months.

Dysport treats deep lines and wrinkles by immobilizing muscles, similar to Botox. Developed in the United Kingdom in the early ’90s, Dysport has been used overseas for many years. Dysport was approved by the Federal Drug Administration in April 2009 for the treatment of head-and-neck muscle spasms and deep lines between the eyebrows.
What You Need To Know About Dysport Vs. Botox
- Dysport is made from the same botulinum toxin Type A as Botox and is injected in the same way as Botox. Both work by temporarily immobilizing muscles, which reduces lines and furrows.
- Dysport is injected around expression lines — the creases caused by frowning, scowling, smiling or looking surprised — to diminish their appearance or to keep them from forming.The three most common areas for Dysport injections are the glabella (area between the eyebrows) for vertical frown lines; across the forehead for horizontal lines that form as we age (our body’s natural attempt to hold up our heavy eyelids); and the “crow’s feet” area where lines form with aging from smiling, squinting and using the muscles in this area. Dysport can improve your appearance and prevent the formation of deep expression lines that make you look older. It will not help fine lines or wrinkles that are not due to facial expressions.
- Dysport has fewer proteins surrounding the toxin and so should stimulate a weaker immune response to break down the toxin. This may make it a good choice for Botox patients who find Botox no longer works because their body has developed antibodies.
- There are some claims that Dysport works faster and lasts longer.

In addition, the FDA has approved Dysport to treat cervical dystonia in adults to reduce the severity of abnormal head position and neck pain caused by the condition.